Lynch Syndrome: An Updated Review

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منابع مشابه

Lynch Syndrome: An Updated Review

Lynch syndrome is one of the most common cancer susceptibility syndromes. Individuals with Lynch syndrome have a 50%-70% lifetime risk of colorectal cancer, 40%-60% risk of endometrial cancer, and increased risks of several other malignancies. It is caused by germline mutations in the DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2. In a subset of patients, Lynch syndrome is caused by 3' end...

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Burning Mouth Syndrome- An Updated Review

Burning Mouth syndrome is a condition characterized by a burning pain or hot sensation which can be localized to the lips or tongue or more widespread in the mouth. The sensation can be continuous or intermittent. It can also be accompanied by other symptoms like dryness, an unpleasant taste, or feelings of numbness. It can increase with talking, eating hot or spicy foods, and in times of stres...

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Biologic Width around Dental Implants: An Updated Review

Soft tissue-implant interface is an important anatomical feature contributing to the long-term success of dental implants. Based on the available evidence, different factors may influence biological width around implants including the surgical technique, implant loading, implant surface properties, abutment materials, implant position, and width of the peri-implant mucosa. The purpose of the pr...

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An Updated Review

Background and Purpose—Rates of stroke incidence and mortality vary across populations with important differences between socioeconomic groups worldwide. Knowledge of existing disparities in stroke risk is important for effective stroke prevention and management strategies. This review updates the evidence for associations between socioeconomic status and stroke. Summary of Review—Studies were ...

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Diagnosing Lynch syndrome

R isk stratification is essential for designing efficacious and cost effective colon cancer screening programmes. One of the most important risk factors for colorectal cancers (CRC) is an inherited predisposition, implicated in 20% of all cases. The spectrum of genetic susceptibility ranges from the low penetrance mutations that modestly increase the colon cancer risk (for example, I 1307K) to ...

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ژورنال

عنوان ژورنال: Genes

سال: 2014

ISSN: 2073-4425

DOI: 10.3390/genes5030497